PPP1R12A anticorps (C-Term)

N° du produit ABIN926675

L’anticorps Lapin Polyclonal anti-PPP1R12A a été validé pour WB. Il convient pour détecter PPP1R12A dans des échantillons de Humain.

Aperçu rapide pour PPP1R12A anticorps (C-Term) (ABIN926675)

Antigène: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R12A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPP1R12A anticorps

Épitope: C-Term

Purification: Purified

Immunogène: PPP1 R11 antibody was raised in rabbit using the C terminal of PPP1 11 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

PPP1R12A Blocking Peptide, (ABIN5615508), is also available for use as a blocking control in assays to test for specificity of this PPP1R12A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PPP1R12A

Antigène: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Autre désignation: PPP1R12A

Sujet: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Synonyms: Polyclonal PPP1R12A antibody, Anti-PPP1R12A antibody, protein phosphatase 1, regulatory, inhibitor subunit 12A antibody, MBS antibody, MGC133042 antibody, MYPT1 antibody.

Pathways: M Phase